Stimulates osteoblast proliferation and builds new bone.
Increases lumbar spine BMD by 9–13%.
Reduces vertebral fractures by 65% and nonvertebral fractures by 53%.
Description
Axiatide — Teriparatide 750 mcg/3ml Anabolic bone-forming agent (PTH 1-34). Stimulates osteoblast proliferation and builds new bone. Increases lumbar spine BMD by 9–13%, reduces vertebral fractures by 65% and nonvertebral fractures by 53%.
Mechanism
Intermittent PTH (1-34) activates cAMP/PKA pathway, promotes osteoblast recruitment & reduces apoptosis. Enhances trabecular connectivity and bone microarchitecture.
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