BUPACIN PLUS - Buparvaquone With Furosemide Injection (Vet)

Each ml contains : Buparvaquone 50 mg Furosemide B.P. 55 mg Sorbitan mono oleate B.P. 100 mg (as preservative) Oil base Q.S.

For the treatment of theileriosis (east coast fever) particularly for advanced cases with pulmonary oedema. Buparvaquone kills theilerial schizonts (in lymphoid cells) and piroplasms (in red blood cells) and it supresses preschizont stages during the Incubation period of disease. Buparvaquone kill the parasite through its actions on their mitochondrial electron transport (respiratory) system. Furosemide is a diuretic, which resolves pulmonary oedema.

Injection by the Intramuscular route into the neck muscles at the rate of 1 ml/20 kg (2.5 mg per kg of buparvaquone and 2.75 mg/kg of furosemide).Repeat after 48 hours. In cases of exceptionally severe infections with pulmonary oedema, further treatment at half the dosage rate may be required at 24 hour interval.

Milk for human consumption should not be taken from animals treated with BUPACIN PLUS until atleast 48 hours after treatment. Milk for animals treated with BUPACIN PLUS is safe for consumption by calves. Animals should not be slaughtered for human consumption until at least 42 days after treatment with BUPACIN PLUS.

Localised swelling may occur at Injection sites but it resolves in a few days. BUPACIN PLUS is very safe so overdosage is unlikely to cause significant adverse effect. BUPACIN PLUS must be administered only by the Intramuscular route. Intravenous Injection may cause severe shock. BUPACIN PLUS is poorly mobilised after subcutaneous injection and its curative effect is greatly reduced. Furosemide is chemically similar to the sulphonamides so BUPACIN PLUS should not be used in animal with sulphonamide sensitivity.